177x Filetype PPTX File size 2.19 MB Source: programme.ias2019.org
Background 8 conventional laboratories serve the whole country needs for viral load with long TAT. Logistics of sample transportation are a bottleneck to achieving optimal results TAT. Point-of-care (POC) test for CD4 and EID have shown positive impact in patient important outcomes. POC for viral load (POCVL) would significantly improve management of HIV+ patients m-PIMA HIV-1/2 VL Test Instrument: Scaled up for EID testing at 130 health facilities. Investigational use only cartridge : Quantitative HIV-1/2 viral load (VL) Requires 50µl of plasma sample Test result in less than 70 min Kit’s volumetric transfer tool simplifies sampling Methods Cross-sectional study in 2 PHCC in Maputo City Sample size: 699 (Women PMTCT cascade) 233 patients for each VL interval (< 1000 cps/ml, 1000- 10000 cps/ml, >10000 cps/ml) 1 microtube 0,5mL venous blood mini-centrifuged (not provided by the manufacturer) for POCVL testing 6 ml EDTA tube- Plasma conventional testing (CAPCTM Roche) 1 DBS card (routine VL in Mozambique) Study Sample Flowchart 500ul for Centrifugation 50ul plasma to with m-pima microtube Mini-centrifuge cartridge 1 EDTA tube DBS Molecular of 6 ml (routine) Centralized lab Testing of INS Remaining Molecular Centrifugation blood Centralized lab and processing of INS
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