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picture1_Methods Of Presentation Pdf 83252 | Mozambique Pocvl Evaluatio Ias2019


 177x       Filetype PPTX       File size 2.19 MB       Source: programme.ias2019.org


File: Methods Of Presentation Pdf 83252 | Mozambique Pocvl Evaluatio Ias2019
background 8 conventional laboratories serve the whole country needs for viral load with long tat logistics of sample transportation are a bottleneck to achieving optimal results tat point of care ...

icon picture PPTX Filetype Power Point PPTX | Posted on 11 Sep 2022 | 3 years ago
Partial capture of text on file.
           Background
  8 conventional laboratories serve the whole 
   country needs for viral load with long TAT.
  Logistics of sample transportation are a bottleneck 
   to achieving optimal results TAT.
  Point-of-care (POC) test for CD4 and EID have 
   shown positive impact in patient important 
   outcomes.
  POC for viral load (POCVL) would significantly 
   improve management of HIV+ patients
       m-PIMA HIV-1/2 VL Test 
  Instrument: Scaled up for EID testing at 130 
   health facilities.
  Investigational use only cartridge : Quantitative 
   HIV-1/2 viral load (VL)
  Requires 50µl of plasma sample 
  Test result in less than 70 min
  Kit’s volumetric transfer tool simplifies sampling
                   Methods
    Cross-sectional study in 2 PHCC in Maputo City
    Sample size: 699 (Women PMTCT cascade)
      233 patients for each VL interval (< 1000 cps/ml, 1000-
       10000 cps/ml, >10000 cps/ml)
    1 microtube 0,5mL venous blood mini-centrifuged 
     (not provided by the manufacturer) for POCVL 
     testing 
    6 ml EDTA tube- Plasma conventional testing 
     (CAPCTM Roche)
    1 DBS card (routine VL in Mozambique)
                    Study Sample Flowchart
                             500ul for             Centrifugation          50ul plasma to 
                                                        with                   m-pima 
                             microtube             Mini-centrifuge            cartridge
      1 EDTA tube               DBS                 Molecular 
         of 6 ml             (routine)            Centralized lab           Testing
                                                      of INS
                            Remaining               Molecular           Centrifugation 
                               blood              Centralized lab       and processing
                                                      of INS
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...Background conventional laboratories serve the whole country needs for viral load with long tat logistics of sample transportation are a bottleneck to achieving optimal results point care poc test cd and eid have shown positive impact in patient important outcomes pocvl would significantly improve management hiv patients m pima vl instrument scaled up testing at health facilities investigational use only cartridge quantitative requires l plasma result less than min kit s volumetric transfer tool simplifies sampling methods cross sectional study phcc maputo city size women pmtct cascade each interval cps ml microtube venous blood mini centrifuged not provided by manufacturer edta tube capctm roche dbs card routine mozambique flowchart ul centrifugation centrifuge molecular centralized lab ins remaining processing...

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