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                                                                                                                                  Chapter
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                                                                                                                                       6
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                              Quantitative Research Designs: 
                              Experimental, Quasi-Experimental, 
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                              and Descriptive
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                              Chapter Outline
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                              ▶    Introduction                                          ▶    Descriptive Quantitative Designs
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                              ▶    Experimental Study Designs                            ▶    Additional Types of Designs
                              ▶    Quasi-Experimental Designs                            ▶    Researcher Interview: Intervention Research,
                                                                                              Dr. Leslie Cunningham-Sabo, PhD, RDN
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                              learning OutCOmes
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                              ▶    Discuss five considerations when planning a           ▶    Discuss the advantages and disadvantages of
                                   research design.                                           various quasi-experimental designs.
                              ▶    Explain the three essential components of             ▶    Compare and contrast the descriptive cross-
                                   experimental designs, and compare and                      sectional, repeated cross-sectional, comparative,
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                                   contrast the following experimental designs:               and descriptive correlational designs.
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                                   randomized controlled trials, crossover, factorial,   ▶    Discuss the advantages and disadvantages of
                                   and Solomon four group designs.                            various descriptive designs.
                              ▶    Discuss the advantages and disadvantages of           ▶    Read a research study and identify the design
                                   various experimental designs.                              used and analyze study results.
                              ▶    Compare and contrast the nonequivalent
                                         © Jones & Bartlett Learning, LLC▶                                        © Jones & Bartlett Learning, LLC
                                   control group and interrupted time series                  Distinguish between secondary data analysis
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                                   designs.                                                   and secondary research.
                              intrOduCtiOn
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                              Designing a research study requires making a number of decisions on the steps you 
                              will take to answer your research question(s). Like an architect, you need to prepare a 
                              blueprint for your project. If you have ever met with an architect before, you know that 
    © Jones & Bartlett Learning, LLC                                         © Jones & Bartlett Learning, LLC                                155
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    © Jones & Bartlett Learning, LLC                                               © Jones & Bartlett Learning, LLC
                  156     Chapter 6: Quantitative Research Designs: Experimental, Quasi-Experimental, and Descriptive
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                                           the process usually starts with a lot of questions. Research design is no different. The 
                                           following questions address a number of key design features that must be considered.
                                            © Jones & Bartlett Learning, LLC                                               © Jones & Bartlett Learning, LLC
                                             1.    What is the research question? Will there be an intervention? Testing the effects of an 
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                                                   intervention is the hallmark of experimental and quasi-experimental research. 
                                                   If there is an intervention with human participants, the researcher will assign 
                                                   participants to be exposed to the independent variable, such as a modified diet or 
                                                   nutrient supplement, or be part of the control group. Experimental and quasi-
                                                   experimental designs are used to test a hypothesis.
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                                             2.    Instead of an intervention, will researchers observe study participants and take measure-
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                                                   ments? For example, researchers might observe a group over a longer period 
                                                   of time to see if exposure to certain factors (such as a diet high in fruits and  
                                                   vegetables) affects their risk of disease. This type of design is called a cohort study 
                                                   design. It is commonly used in the field of epidemiology, a discipline within 
                                                   public health that looks at the rates of health-related states (such as disease) in dif-
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                                                   ferent groups of people and why they occur, and then looks at how this informa-
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                                                   tion can be used to control health problems. Study designs used in epidemiology 
                                                   are discussed in Chapter 7.
                                             3.    What are the variables? What comparisons are going to be made between or within 
                                                   groups? Comparisons are needed to examine relationships between the indepen-
                                                   dent and the dependent variable.
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                                             4.    When and how often will data be collected or measurements taken? Many experimental 
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                                                   studies measure the dependent variable at least before and after the intervention. 
                                                   Weight loss studies, for example, often take measurements for a year or more 
                                                   to see whether participants kept the weight off. Data may be collected at just 
                                                   one point in time, such as in a cross-sectional study, or more frequently. In a  
                                                   longitudinal study, participants are observed and measurements are taken over 
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                                                   a long period of time. Longitudinal studies either go forward in time (prospec-
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                                                   tive) or backward in time (retrospective).
                                             5.    What will the setting be for the study? The setting could be a hospital, community 
                                                   center, or other location. Some studies use multiple sites.
                                             6.    In an intervention study with at least two groups, will the participants be randomly assigned 
                                                   to a group? True experimental research involves random assignment to groups 
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                                                   so participants each have an equal chance of receiving any of the treatments 
                                                   (including no treatment) under study. Quasi-experimental research does not 
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                                                   have randomization of participants to groups.
                                              7.   In a human intervention study, will participants, researchers, and staff be blinded from 
                                                   knowing to which group a participant was assigned? Blinding helps to prevent or 
                                                   minimize sources of bias, such as expectation bias. Expectation bias is when 
                                            © Jones & Bartlett Learning, LLC                                               © Jones & Bartlett Learning, LLC
                                                   researchers’ expectations of what they believe the study results should be get in 
                                                   the way of accurately taking measurements and reporting results.
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                                             8.    What controls will be put in place to reduce the influence of extraneous variables? Extra-
                                                   neous variables are factors outside of the variables being studied that might 
                                                   influence the outcome of a study and cause incorrect conclusions. A good quan-
                                                   titative design identifies and rules out as many of these competing explanations 
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                                                   as possible.
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                                           A good research design helps you answer the research question while effectively reducing 
                                           threats to design validity.
                                                Quantitative research designs are often used to look at causal relationships, but they 
                                           can also be used to look at associations or relationship between variables. Quantitative 
                                           research studies can be placed into one of five categories, although some categories do vary 
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                                                                                                                                                                                                                                                                                                                                                                                         Experimental Study Designs                                                                               157
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                                                                                                       a bit from book to book. First are  experimental designs  with an intervention, control 
                                                                                                       group, and randomization of participants into groups. Next are  quasi-experimental 
                                                                                                       designs  with an intervention but no randomization.  Descriptive designs  do not have 
                                                                                                                                         © Jones & Bartlett Learning, LLC                                                                                                                                                                                                                            © Jones & Bartlett Learning, LLC
                                                                                                       an intervention or treatment and are considered nonexperimental. They usually aim to 
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                                                                                                       provide information about relevant variables but do not test hypotheses. Good descrip-
                                                                                                       tive studies provoke the “why” questions of analytic (cause-and-effect) research. Two 
                                                                                                       additional categories are epidemiologic and predictive correlational designs. 
                                                                                                                        When you read about designs in this chapter, examples of studies are given to illus-
                                                                                                       trate the design. The examples include some discussion of the results of statistical tests, 
                                                                           © Jones & Bartlett Learning, LLC                                                                                                                                                                                                                           © Jones & Bartlett Learning, LLC
                                                                                                       as well as sample tables from the studies. In a quantitative study, statistics are often used 
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                                                                                                       to answer one of these questions: 
                                                                                                               1.                   Is    there  a   difference  among the groups? 
                                                                                                                                  Example: “LA Sprouts: A Garden-Based Nutrition Intervention Pilot Pro-
                                                                                                                                 gram Influences Motivation and Preferences for Fruits and Vegetables in Latino 
           © Jones & Bartlett Learning, LLC                                                                                                                                                                                                                            © Jones & Bartlett Learning, LLC
                                                                                                                                 Youth” ( Journal of    the Academy of Nutrition and Dietetics ,  2012)   
                                                                                                               2.                 Is there an  association  or relationship among the variables?   
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                                                                                                                                  Example: “Preventable Incidence and Mortality of Carcinoma Associated With 
                                                                                                                                 Lifestyle Factors Among White Adults in the United States” ( JAMA Oncology , 
                                                                                                                                 2016)   
                                                                                                        You can often tell from the title of an article whether the study is looking at differences 
                                                                                                                                         © Jones & Bartlett Learning, LLC                                                                                                                                                                                                                            © Jones & Bartlett Learning, LLC
                                                                                                       among groups or an association among variables. 
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                                                                                                                        Experimental and quasi-experimental designs have an intervention, so they involve 
                                                                                                       questions about differences—often the difference between an outcome measured in the 
                                                                                                       experimental and control groups. Correlational studies look at associations.  Table 6.1  
                                                                                                       shows examples of statistics that may be used to answer these two questions.     
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                                                                                                                                                               TIP 
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                                                                                                                                                               When you read a study, first read the abstract to determine whether there is an intervention. If so, 
                                                                                                                                                              the study is either experimental or quasi-experimental. If not, the study will fit into one of the other 
                                                                                                                       categories. If you see the word “association” in the title, the study is likely to be a descriptive, epidemiological, 
           © Jones & Bartlett Learning, LLC                                                                                                                                                                                                                            © Jones & Bartlett Learning, LLC
                                                                                                                       or predictive correlation design. 
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                                                                                                        experimental study designs 
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                                                                                                        To be considered an experimental design, the following must be present. 
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                                                                                                               1.                An intervention or treatment . The researcher manipulates the independent variable 
                                                                                                                                 by, for example, requiring the intervention group to eat a diet that has been 
                                                                                                                                 modified, take a supplement containing a nutrient or phytochemical, or take part 
                                                                                                                                 in an educational program.   
                                                                                                               2.                Control for extraneous variables . Various control techniques, such as randomiza-
                                                                         © Jones & Bartlett Learning, LLC                                                                                                                                                                                                                            © Jones & Bartlett Learning, LLC
                                                                                                                                 tion and having a control group, are used. Having a control group allows the 
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                                                                                                                                 researcher to compare and evaluate the performance of the experimental group 
                                                                                                                                 on the outcome (dependent) variable.   
                                                                                                               3.                Randomization  . The researcher randomly assigns each participant to a group so 
                                                                                                                                 that each person has an equal chance of being in either group. This removes the 
                                                                                                                                 problem of selection bias so that comparable, balanced groups of similar size are 
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                 158     Chapter 6: Quantitative Research Designs: Experimental, Quasi-Experimental, and Descriptive
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                  Table 6.1 Statistics That Look at Differences and Statistics That Look at Associations
                                                            Statistics That Look at Differences
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                                                                                                                      Measurement 
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                                             Test                                                                   level of dependent 
                          Name             statistic               Purpose                  Number of groups             variable
                  Independent samples  t              To test the difference between      2                       Interval/ratio
                  t-test                              the means of two independent 
                       © Jones & Bartlett Learning, LLC                                             © Jones & Bartlett Learning, LLC
                                                      groups.
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                  Paired samples t-test  t            To test the difference between      2                       Interval/ratio
                  (or dependent t-test)               the means from two paired 
                                                      groups (such as before-and-
                                                      after observations on the same 
    © Jones & Bartlett Learning, LLCsubject).                                   © Jones & Bartlett Learning, LLC
                  One-way analysis of     F           To test the difference among        More than two           Interval/ratio
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                  variance (ANOVA)                    means of more than two              groups
                                                      independent groups for one 
                                                      independent variable (with more 
                                                      than one level).
                  Two-way analysis of     F           To test the difference among        More than two           Interval/ratio
                                          © Jones & Bartlett Learning, LLC                                             © Jones & Bartlett Learning, LLC
                  variance (ANOVA)                    means for two independent           groups
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                                                      variables, of which each can have 
                                                      multiple levels.
                  Repeated measures       F           To test the difference among        One group               Interval/ratio
                  ANOVA (one-way                      three or more means in the 
                  within-subjects)                    same group over time. (Extended 
                       © Jones & Bartlett Learning, LLC                                            © Jones & Bartlett Learning, LLC
                                                      design of dependent samples 
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                                                      t-test).
                  Chi-square              χ2          To analyze nominal and ordinal      Two or more groups      Nominal/Ordinal
                                                      data to find differences between 
                                                      groups.
                                                           Statistics That Look at Associations
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                                                                                                                      Measurement 
                                             Test                                                                   level of dependent 
                          Name             statistic                           Purpose                                   variable
                  Pearson product-        r           To measure the strength and direction of the relationship  Interval/ratio
                  moment correlation                  between two variables.
                                          © Jones & Bartlett Learning, LLC                                             © Jones & Bartlett Learning, LLC
                  Spearman rank-          ρ           To measure the strength and direction of the relationship  Ordinal, interval, or 
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                  order correlation                   between two variables. (Nonparametric version of            ratio
                                                      Pearson product-moment correlation)
                  Linear regression                   To predict the value of a dependent variable and            Interval/ratio
                                                      measure the size of the effect of the independent 
                       © Jones & Bartlett Learning, LLC                                            © Jones & Bartlett Learning, LLC
                                                      variable on a dependent variable while controlling for 
                                                      covariates.
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                  Logistic regression                 Same as linear regression; used when dependent value        Binary/dichotomous
                                                      is binary.
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